Robbee Wedow, PhD, will present and discuss his HGG Advances paper on genetics curriculum to refute genetic essentialism.

Drs. Theodore Drivas and Jessica Gold will discuss a large retrospective study of over 14,000 adults evaluating how race and social determinants of health influence access to adult genetics clinics, genetic testing decisions, and diagnostic outcomes. The paper reveals striking disparities in who is evaluated for genetics care—and who ultimately benefits from testing.

Dr. Noura Abul-Husn and Sabrina Suckiel will discuss healthcare provider experiences returning monogenic, polygenic, and integrated risk results for common chronic conditions in the eMERGE study. Key findings from a cross-sectional survey of study providers involved in result disclosure highlight differences in confidence and perceived complexity across genomic risk types, as well as key considerations and challenges in communicating polygenic and integrated risk scores.

Kyle Retterer, MS, Chief Data Science Officer at Geisinger, will discuss scalable methods for genomic-first ascertainment of rare disorders and the results of applying these methods to a healthcare population of over 200,000 study participants.

November HGG Advances Journal Club presented by Joanna Melia, MD