Dr. Sara Cromer and Dr. David Conti will review the commonly used population descriptors, polygenic scores, and social determinants of health measures, identifying the nuances in measurement and interpretation. They will then turn to analytic and ethical considerations for modeling polygenic risk and SDoH jointly across diverse populations.

ASHG’s 2026 Cardiogenetics Symposium

Robbee Wedow, PhD, will present and discuss his HGG Advances paper on genetics curriculum to refute genetic essentialism.

Drs. Theodore Drivas and Jessica Gold will discuss a large retrospective study of over 14,000 adults evaluating how race and social determinants of health influence access to adult genetics clinics, genetic testing decisions, and diagnostic outcomes. The paper reveals striking disparities in who is evaluated for genetics care—and who ultimately benefits from testing.

In this upcoming Bioinformatics and Computational Methods Shared Interest Group (SIG) Seminar, Dr. Fritz Sedlazeck will present on mosaic structural variants (SVs) and tandem repeat (TR) mutations, as well as introduce a new extension of Sniffles, an SV caller.