The commonality of TSPEAR-related ARED14 sheds light on human origins

Adam Jackson is an academic clinical fellow in clinical genetics at the Manchester Centre for Genomic Medicine, UK.  He obtained his medical degree from the University of Manchester in 2013 prior to starting clinical rotations in both adult and paediatric medicine in the North West of England before obtaining Membership of the Royal Colleges of Physicians (MRCP) in 2018.  He obtained a Master’s degree in Genomic Medicine in 2017 and is currently completing his PhD studies on genomics of rare diseases.  In March 2023, he was awarded the Robin-Winter prize from the UK Clinical genetics Society. 

Siddharth Banka is a Professor of Genomic Medicine and Rare Diseases at the University of Manchester, and a Consultant Clinical Geneticist at Saint Mary’s Hospital in Manchester. His research interest is in neurodevelopmental and congenital malformation disorders caused by defects in chromatin remodelling genes, copy number variations and inborn errors of metabolism. His group has led, or contributed to, the discoveries of ~50 novel genetic diseases. Using a combination of cellular and organismal models and benefiting from extensive internal, national and international collaborations his group has defined underlying mechanisms of several rare disorders. His research has a direct and immediate impact on health by improving diagnosis, management and treatments for patients, while simultaneously revealing fundamental biological insights. In his clinical practice I see children and adults with a range of genetic disorders. Overall, the aim of his work is to improve diagnosis, management, and treatments of patients with rare diseases.