Enhanced genetic diagnosis through RNA-seq analysis of transdifferentiated cells

Dr. Pengfei Liu is Associate Professor (tenured) at the Department of Molecular and Human Genetics at Baylor College of Medicine, as well as the CLIA Lab Director of the Medical Genetics and Multiomics Laboratory at Baylor. He is also the Director of the Baylor ACGME/ABMGG Laboratory Genetics and Genomics (LGG) Fellowship Program. Dr. Liu is a board-certified PhD clinical geneticist with a primary research interest in translating new technologies into clinical testing to advance the diagnostics and therapy of rare diseases. His clinical work has provided key evidence to recognize the necessity and importance of clinical reanalysis of diagnostic exome data. Dr. Liu has led the launch of clinical whole genome sequencing at Baylor Genetics as well as the clinical RNA-seq for the Undiagnosed Diseases Network (UDN). He has received multiple honors and awards, including the Michael Watson’s Genome Medicine Innovation Award from the ACMG, the Genomic Innovator Award from the NHGRI, and the Cotterman Award from the ASHG.