
Alz in the Details: Piecing Together the Alzheimer's Puzzle
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This session covers recent advances linking transcriptional states to clinical phenotypes to enhance our understanding of pathogenesis in Alzheimer's disease through epigenetic, single cell, and spatial -omics methods. Talks include large-scale studies of gene expression, RNA editing and somatic mutations in AD tissues.
Learning Objectives
* Identify potential molecular mechanisms driving the progression from primary age-related tauopathy to Alzheimer's disease
* Evaluate the functional roles of somatic mutations and RNA editing in Alzheimer's Disease